Suspicion of pituitary microadenomas
Question: Oleg. I am 30 years old. Since January 2006, menstruation became scarce (this is common, there is no delay), has put on weight (from 54 kg in the growth of 174 to 59 kg) revealed a uterine myoma (visible on the ultrasound, the size of 11mm). In June 2006, we started strong edema (the entire body, especially the legs). Was investigated by nephrologist, cardiologist, vascular surgeon (they did not reveal any pathology). Did a pituitary MRI (with contrast), MRI and tests for adrenal hormones (in dynamics). Conclusion MRI: we can not exclude the left half of microadenomas adenohypophysis (… The structure of its non-uniform due to the presence in the left half of the adenohypophysis of low-intensity signal on T1 WI with fuzzy contours, size 0,3 x0, 3 cm…). Tests on hormones: prolactin, LH, FSH, TSH, estradiol, progesterone, testosterone, free androgen index, DEAS. All figures are within normal limits, except for LH, which also returned to normal with the passage of time: June 06 year-7, 46 (0,5-5); July 06-6,7 (0,5-5), August 06-4, 6 (1,1-8,7); October 06-5,4 (1,1-8,7). Has to neurosurgeons (their are excluded), endocrinologists. Gynecology, endocrinologist appointed simultaneous reception of hormones: levothyroxine (0,25), parlodel, proginova and utrozhestan. Not daring to take all medications at once, began to drink levothyroxine (reduced edema, for this reason I accept it for six months). Endocrinologists strongly against such an appointment (as the deviations are not discovered by the tests, the acceptance of such products as gormanalnyh parlodel and thyroxine they consider unnecessary). I tried to stop taking levothyroxine, enhanced swelling, I began to drink again. Currently, my condition continued: scanty menstruation for 1-2 days against the normal cycle (average 28 days), swelling, constant acne. Is the appointment of a gynecologist, endocrinologist? In what may be the reason for the scarcity of menstruation and edema (no doctor, looking at test results, the specific reason could not understand)? Do these symptoms are a consequence of the presence of pituitary adenoma (neurosurgeons and endocrinologists have my doubts about its presence)? Are the results as an increase in adenoma or it is asymptomatic? Thank you in advance and hope for your help.
Answer: 1. Appointment of L-thyroxine with normal TSH (reflected in the lack or excess of thyroid hormones) does not make sense. 2. With respect to adenoma: the suspicion does not mean the presence, so if there is no evidence – should not give it much attention. Adenoma could affect your medical condition, highlighting or other hormones (most often – prolactin), but their levels are normal, and many diseases can be seen on the clinical manifestations of inspection endocrinologist – apparently expressed no change, so the diagnosis of some serious endocrine disease you do not call. 3. The main thing – the regularity of the menstrual cycle. Scanty allocation can be and are normal, and attribute some of the changes in the ovaries (those can be judged from the Basal body temperature), but not always such a situation requires active medical intervention in the hormonal system. At least, the cause of overweight violations of the ovaries are not (although, conversely, may be the result of excess weight). More specifically at a distance to judge very difficult: (